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MultiTarget Pharmaceuticals coriloxin
Influence of <t>coriloxin</t> on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.
Coriloxin, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/coriloxin/product/MultiTarget Pharmaceuticals
Average 90 stars, based on 1 article reviews
coriloxin - by Bioz Stars, 2026-04
90/100 stars

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1) Product Images from "Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells"

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

Journal: International Journal of Molecular Sciences

doi: 10.3390/ijms23073991

Influence of coriloxin on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.
Figure Legend Snippet: Influence of coriloxin on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.

Techniques Used: Isolation, MTT Assay, Solvent, Control

Antiproliferative effects of coriloxin on lung cancer cells. The proliferation activity of ( A ) A549 and ( B ) CL1-5 cells ( n = 6 per group) treated with coriloxin for 24, 48, or 72 h was examined. Each experiment was performed, at least, in triplicate, and the values were reported as mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO).
Figure Legend Snippet: Antiproliferative effects of coriloxin on lung cancer cells. The proliferation activity of ( A ) A549 and ( B ) CL1-5 cells ( n = 6 per group) treated with coriloxin for 24, 48, or 72 h was examined. Each experiment was performed, at least, in triplicate, and the values were reported as mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO).

Techniques Used: Activity Assay, Solvent, Control

Anticlonogenic effects of coriloxin on CL1-5 cells. Representative images and integrated results of cells ( n = 4 per group) under the ( A ) anchorage-dependent and ( B ) anchorage-independent clonogenic assays are presented. The graphs summarize the analytical results. Values are reported as means ±SD ( n ≥ 3). * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). Scale bars, 1 cm.
Figure Legend Snippet: Anticlonogenic effects of coriloxin on CL1-5 cells. Representative images and integrated results of cells ( n = 4 per group) under the ( A ) anchorage-dependent and ( B ) anchorage-independent clonogenic assays are presented. The graphs summarize the analytical results. Values are reported as means ±SD ( n ≥ 3). * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). Scale bars, 1 cm.

Techniques Used: Solvent, Control

Antimigratory and anti-invasive effects of coriloxin on CL1-5 cells. ( A ) Wound-healing assay of the coriloxin-treated CL1-5 cells. We counted cells migrating into the wound area 4 and 8 h after wounding. ( B ) Cell invasion effects exerted by coriloxin (indicated concentrations). The data are representative of three independent experiments and are indicated as the mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). ( C ) Gelatin zymography assay of MMP-2 and MMP-9 activities in coriloxin-treated cells.
Figure Legend Snippet: Antimigratory and anti-invasive effects of coriloxin on CL1-5 cells. ( A ) Wound-healing assay of the coriloxin-treated CL1-5 cells. We counted cells migrating into the wound area 4 and 8 h after wounding. ( B ) Cell invasion effects exerted by coriloxin (indicated concentrations). The data are representative of three independent experiments and are indicated as the mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). ( C ) Gelatin zymography assay of MMP-2 and MMP-9 activities in coriloxin-treated cells.

Techniques Used: Wound Healing Assay, Solvent, Control, Zymography Assay

Effects of coriloxin treatment on ERK/AKT and the expression of EMT-related proteins in CL1-5 cells, as determined through Western blot analysis. ( A ) Effects of coriloxin on p-ERK1/2, ERK2, p-AKT, and AKT levels. Cells were treated with 10 µM coriloxin or 0.01% DMSO (solvent control), after which Western blotting revealed the protein expression levels. ( B ) Protein levels of EMT-related genes (Vimentin, N-cad, and E-cad) in CL1-5 cells subjected to 48 h coriloxin treatment (at indicated concentrations). The solvent control group was exposed to 0.01% DMSO. The loading controls were GADPH or α-tubulin. Each experiment was performed, at least, in duplicate.
Figure Legend Snippet: Effects of coriloxin treatment on ERK/AKT and the expression of EMT-related proteins in CL1-5 cells, as determined through Western blot analysis. ( A ) Effects of coriloxin on p-ERK1/2, ERK2, p-AKT, and AKT levels. Cells were treated with 10 µM coriloxin or 0.01% DMSO (solvent control), after which Western blotting revealed the protein expression levels. ( B ) Protein levels of EMT-related genes (Vimentin, N-cad, and E-cad) in CL1-5 cells subjected to 48 h coriloxin treatment (at indicated concentrations). The solvent control group was exposed to 0.01% DMSO. The loading controls were GADPH or α-tubulin. Each experiment was performed, at least, in duplicate.

Techniques Used: Expressing, Western Blot, Solvent, Control



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MultiTarget Pharmaceuticals coriloxin
Influence of <t>coriloxin</t> on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.
Coriloxin, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/coriloxin/product/MultiTarget Pharmaceuticals
Average 90 stars, based on 1 article reviews
coriloxin - by Bioz Stars, 2026-04
90/100 stars
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Influence of coriloxin on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.

Journal: International Journal of Molecular Sciences

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

doi: 10.3390/ijms23073991

Figure Lengend Snippet: Influence of coriloxin on BEAS2B, A549, and CL1-5 cell viability. ( A ) Chemical composition of the isolated coriloxin. Following treatment with various concentrations of coriloxin, ( B ) BEAS2B, ( C ) A549, and ( D ) CL1-5 cells were subjected to the MTT assay. Results shown are percentages of the solvent control group (0.01% DMSO). These results are representative of two independent experiments performed, at least, in triplicate. Data are expressed as mean ±SD.

Article Snippet: The findings suggest that coriloxin has potential for application to cancer treatment as a multitarget agent.

Techniques: Isolation, MTT Assay, Solvent, Control

Antiproliferative effects of coriloxin on lung cancer cells. The proliferation activity of ( A ) A549 and ( B ) CL1-5 cells ( n = 6 per group) treated with coriloxin for 24, 48, or 72 h was examined. Each experiment was performed, at least, in triplicate, and the values were reported as mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO).

Journal: International Journal of Molecular Sciences

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

doi: 10.3390/ijms23073991

Figure Lengend Snippet: Antiproliferative effects of coriloxin on lung cancer cells. The proliferation activity of ( A ) A549 and ( B ) CL1-5 cells ( n = 6 per group) treated with coriloxin for 24, 48, or 72 h was examined. Each experiment was performed, at least, in triplicate, and the values were reported as mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO).

Article Snippet: The findings suggest that coriloxin has potential for application to cancer treatment as a multitarget agent.

Techniques: Activity Assay, Solvent, Control

Anticlonogenic effects of coriloxin on CL1-5 cells. Representative images and integrated results of cells ( n = 4 per group) under the ( A ) anchorage-dependent and ( B ) anchorage-independent clonogenic assays are presented. The graphs summarize the analytical results. Values are reported as means ±SD ( n ≥ 3). * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). Scale bars, 1 cm.

Journal: International Journal of Molecular Sciences

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

doi: 10.3390/ijms23073991

Figure Lengend Snippet: Anticlonogenic effects of coriloxin on CL1-5 cells. Representative images and integrated results of cells ( n = 4 per group) under the ( A ) anchorage-dependent and ( B ) anchorage-independent clonogenic assays are presented. The graphs summarize the analytical results. Values are reported as means ±SD ( n ≥ 3). * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). Scale bars, 1 cm.

Article Snippet: The findings suggest that coriloxin has potential for application to cancer treatment as a multitarget agent.

Techniques: Solvent, Control

Antimigratory and anti-invasive effects of coriloxin on CL1-5 cells. ( A ) Wound-healing assay of the coriloxin-treated CL1-5 cells. We counted cells migrating into the wound area 4 and 8 h after wounding. ( B ) Cell invasion effects exerted by coriloxin (indicated concentrations). The data are representative of three independent experiments and are indicated as the mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). ( C ) Gelatin zymography assay of MMP-2 and MMP-9 activities in coriloxin-treated cells.

Journal: International Journal of Molecular Sciences

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

doi: 10.3390/ijms23073991

Figure Lengend Snippet: Antimigratory and anti-invasive effects of coriloxin on CL1-5 cells. ( A ) Wound-healing assay of the coriloxin-treated CL1-5 cells. We counted cells migrating into the wound area 4 and 8 h after wounding. ( B ) Cell invasion effects exerted by coriloxin (indicated concentrations). The data are representative of three independent experiments and are indicated as the mean ± SD. * p < 0.05 indicates a significant difference from the solvent control group (0.01% DMSO). ( C ) Gelatin zymography assay of MMP-2 and MMP-9 activities in coriloxin-treated cells.

Article Snippet: The findings suggest that coriloxin has potential for application to cancer treatment as a multitarget agent.

Techniques: Wound Healing Assay, Solvent, Control, Zymography Assay

Effects of coriloxin treatment on ERK/AKT and the expression of EMT-related proteins in CL1-5 cells, as determined through Western blot analysis. ( A ) Effects of coriloxin on p-ERK1/2, ERK2, p-AKT, and AKT levels. Cells were treated with 10 µM coriloxin or 0.01% DMSO (solvent control), after which Western blotting revealed the protein expression levels. ( B ) Protein levels of EMT-related genes (Vimentin, N-cad, and E-cad) in CL1-5 cells subjected to 48 h coriloxin treatment (at indicated concentrations). The solvent control group was exposed to 0.01% DMSO. The loading controls were GADPH or α-tubulin. Each experiment was performed, at least, in duplicate.

Journal: International Journal of Molecular Sciences

Article Title: Coriloxin Exerts Antitumor Effects in Human Lung Adenocarcinoma Cells

doi: 10.3390/ijms23073991

Figure Lengend Snippet: Effects of coriloxin treatment on ERK/AKT and the expression of EMT-related proteins in CL1-5 cells, as determined through Western blot analysis. ( A ) Effects of coriloxin on p-ERK1/2, ERK2, p-AKT, and AKT levels. Cells were treated with 10 µM coriloxin or 0.01% DMSO (solvent control), after which Western blotting revealed the protein expression levels. ( B ) Protein levels of EMT-related genes (Vimentin, N-cad, and E-cad) in CL1-5 cells subjected to 48 h coriloxin treatment (at indicated concentrations). The solvent control group was exposed to 0.01% DMSO. The loading controls were GADPH or α-tubulin. Each experiment was performed, at least, in duplicate.

Article Snippet: The findings suggest that coriloxin has potential for application to cancer treatment as a multitarget agent.

Techniques: Expressing, Western Blot, Solvent, Control